Glyphosate and glyphosate-based herbicides contribute to autoimmune disease by causing dysbiosis in the microbiome and contributing to intestinal permeability (aka "leaky gut"). When the blood-gut barrier becomes faulty, toxins are released from the gut into the bloodstream, creating a cascade of inflammation and immune response. In the case of autoimmunity, the immune system then mistakenly attacks the organs of the body.

Glyphosate has been shown to cause damage to the microbiome, selectively harming beneficial strains while sparing more pathogenic bacteria. The scientific literature is rapidly expanding as we gain greater understanding of just how critical the composition is of our microbiome to preventing disease and thriving. And how dietary exposure to glyphosate is a key piece of the puzzle of the explosion in chronic disease.

Low-dose glyphosate exposure alters gut microbiota composition and modulates gut homeostasis

 

Use of Shotgun Metagenomics and Metabolomics to Evaluate the Impact of Glyphosate or Roundup MON 52276 on the Gut Microbiota and Serum Metabolome of Sprague-Dawley Rats

 

Glyphosate and its formulations Roundup Bioflow and RangerPro alter bacterial and fungal community composition in the rat caecum microbiome

 

Alterations in human gut microbiome composition and metabolism after exposure to glyphosate and Roundup and/or a spore-based formulation using the SHIME® technology

 

The Ramazzini Institute 13-week pilot study on glyphosate and Roundup administered at human-equivalent dose to Sprague Dawley rats: effects on the microbiome

 

Glyphosate-based-herbicide exposure affects gut microbiota, anxiety and depression-like behaviors in mice

 

Sex-dependent impact of Roundup on the rat gut microbiome